COAGULOME AND TUMOR MICROENVIRONMENT: IMPACT OF ONCOGENES, CELLULAR HETEROGENEITY AND EXTRACELLULAR VESICLES


Genetic engineering of cotton with a novel cry2AX1 gene to impart insect resistance against Helicoverpa armigera

Embryogenic calli of cotton (Coker310) were cocultivated with the Agrobacterium tumefaciens strain LBA4404 harbouring the codon-optimised, chimeric cry2AX1 gene consisting of sequences from cry2Aa and cry2Ac genes isolated from Indian strains of Bacillus thuringiensis.Forty-eight putative transgenic plants were regenerated, and PCR analysis of thes

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Fluconazole Failure in the Treatment of Coccidioidal Meningitis

Introduction: Coccidioidal meningitis (CM) is the most lethal form of disseminated coccidioidomycosis.Current guidelines recommend fluconazole as initial therapy but 7NP there has been a paucity of data regarding failure of fluconazole and optimal fluconazole dosage in the treatment of CM.We conducted this study to understand risk factors for fluco

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